The region covers a geographical area of approximately 18,478 square kilometres. This constitutes about 12.7 per cent of the total land area of Ghana. The region is bordered on the North by the Republic of Burkina Faso, on the East by Upper East Region, on the South by Northern Region and on the West by Cote d’Ivoire.The region is located in the guinea savannah vegetation belt.
The vegetation consists of grass with scattered drought resistant trees such as the shea, the baobab, dawadawa, and neem trees. The heterogeneous collection of trees provides all domestic requirements for fuel wood and charcoal, construction of houses, cattle kraals and fencing of gardens. The shorter shrubs and grass provide fodder for livestock.
The population of the region according to 2010 Population and Housing Census stands at 702,110 with 341,182 male and 360,928 female.